Early Effects of Sleeve Gastrectomy on Ambulatory Blood Pressure and Protenuria

Early Effects of Sleeve Gastrectomy

Abstract

Aim:

Obesity  is  increasing  in  prevalence  worldwide  is  a  serious  health problem   that   causes   significant   morbidity   and   mortality.   One   of   these   morbidity   is hypertension. Our aim is to perform  laparoscopic sleeve gastrectomy on obese patients and to observe  the  effects  of  surgery  on  ambulatory  blood  pressure  and  dipper  or  non-dipper hypertension.  Also  we  evaluate  the  effect  of laparoscopic  sleeve gastrectomy on biochemical parameters   such  as spot  urine creatinine  and protein ratio, fasting glucose.

Material and methods

 44  patients  which  laparoscopic  sleeve  gastrectomy  planned  by  reason  of obesity were  included  in  the  study.  Ambulatory  blood  pressure  monitoring  has  been  recorded  for obese   patients   before   surgery  and   after   surgery   for   three   months. Demographic  data  and  laboratory  tests  were  scanned  and  saved  before  surgery  and  three months after the surgery.

Results:

 After  laparoscopic  sleeve  gastrectomy  surgery,  at  the  end  of  the  third  month, significant   decrease   on   the   daytime   diastolic   and   nighttime  systolic  and   diastolic  blood pressure on ambulatory blood pressure monitoring measurements has been observed. Also, we found  a  negative  correlation  between  weight  loss  and  diastolic blood  pressure.  After the surgery; the usage  of  antihypertensive  medicines  are  decreased  remarkably  in  comparison  with  before surgery.  Indeed;  spot  urine  protein/creatinine  ratio  declined  significantly  for  patients  at  the end  of third  month  after surgery.  At the same time; white blood  count,  neutrophils,  platelet counts and fasting  blood sugar are decreased.

Conclusions:

After  such  a  short  time  as  three  months  of  laparoscopic  sleeve  gastrectomy surgery,  blood pressure and proteinuria decreased in morbid  obese remarkably.