Early Effects of Sleeve Gastrectomy on Ambulatory Blood Pressure and Protenuria
Early Effects of Sleeve Gastrectomy
Keywords:ABPM, laparoscopic sleeve gastrectomy, obesity, proteinuria
Obesity is increasing in prevalence worldwide is a serious health problem that causes significant morbidity and mortality. One of these morbidity is hypertension. Our aim is to perform laparoscopic sleeve gastrectomy on obese patients and to observe the effects of surgery on ambulatory blood pressure and dipper or non-dipper hypertension. Also we evaluate the effect of laparoscopic sleeve gastrectomy on biochemical parameters such as spot urine creatinine and protein ratio, fasting glucose.
Material and methods
44 patients which laparoscopic sleeve gastrectomy planned by reason of obesity were included in the study. Ambulatory blood pressure monitoring has been recorded for obese patients before surgery and after surgery for three months. Demographic data and laboratory tests were scanned and saved before surgery and three months after the surgery.
After laparoscopic sleeve gastrectomy surgery, at the end of the third month, significant decrease on the daytime diastolic and nighttime systolic and diastolic blood pressure on ambulatory blood pressure monitoring measurements has been observed. Also, we found a negative correlation between weight loss and diastolic blood pressure. After the surgery; the usage of antihypertensive medicines are decreased remarkably in comparison with before surgery. Indeed; spot urine protein/creatinine ratio declined significantly for patients at the end of third month after surgery. At the same time; white blood count, neutrophils, platelet counts and fasting blood sugar are decreased.
After such a short time as three months of laparoscopic sleeve gastrectomy surgery, blood pressure and proteinuria decreased in morbid obese remarkably.
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