COVID-19 HASTALARINDA BİYOKİMYASAL, İNFLAMATUAR VE HEMATOLOJİK PARAMETRELERİN DEĞERLENDİRİLMESİ: COVID-19 HASTALARINDA BİYOKİMYASAL, İNFLAMATUAR VE HEMATOLOJİK PARAMETRELERİN DEĞERLENDİRİLMESİ

ayşe Umay Çalışır; Birsen Aydın; Sirin Cetin; meryem Çetin

doi:10.5281/zenodo.14032663

Authors

ayşe Umay Çalışır Amasya Üniversitesi
Birsen Aydın Amasya Üniversitesi
Sirin Cetin
meryem Çetin Amasya Üniversitesi

DOI:

https://doi.org/10.5281/zenodo.14032663

Keywords:

COVID-19, age, gender, laboratory parameters

Abstract

Aim: This study aims to evaluate the effects of demographic
factors such as age and gender on routine laboratory parameters
in COVID-19 patients. COVID-19 disease can exhibit a wide range of
clinical findings, from mild symptoms to critical multiorgan failure.
In this context, the role of biochemical markers in predicting the
prognosis of the disease is very important.
Material and Method: In the study, biochemical parameters
evaluating liver, kidney and heart functions and inflammation
markers were analyzed in COVID-19 patients depending on age
and gender.
Results: Uric acid, Blood urea nitrogen (BUN), Lactate
dehydrogenase (LDH), Potassium, C-reactive protein (CRP), CRP/
Lymphocyte ratio (CLR), Neutrophil/Lymphocyte ratio (NLR),
D-Dimer, Monocyte count (MONO), Fibrinogen, Hematocrit (HCT),
White blood cells (WBC), Neutrophil count (NEU) and Platelet
distribution width (PDW) parameters were positively correlated
with age. In addition, De Ritis ratio (AST/ALT), sodium, Gromerular
filtration rate (EFGR), Red blood cells (RBC), Hemoglobin (HBG) and
Eosinophil count (EOS) were negatively correlated with age. In
addition, thrombosis-related markers such as thrombocytopenia
and hypercoagulation increased with age.
Conclusion: Our study reveals that inflammatory markers and
organ function deteriorations become evident with age in
COVID-19 patients. It can be concluded that elderly patients
should be closely monitored and that parameters that show
very significant correlation in the findings section can be used as
markers to evaluate the prognosis of the disease in this group.

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Evaluation of Biochemical, Inflammatory, and Hematological Parameters in COVID-19 Patients