Clinical Insights into Developmental Dysplasia of the Hip: Risk Factors and Findings from a Turkish Pediatric Study
DDH Risk Factors: Insights from a Turkish Pediatric Study
DOI:
https://doi.org/10.5281/zenodo.10018988Keywords:
Developmental dysplasia of the hip,, risk factors, twinning, first-born, prematurity, C-sectionAbstract
Background: Limited research exists regarding the connection between developmental dysplasia of the hip (DDH) and risk factors within the Turkish population.
Objective: This study aimed to explore the potential associations between DDH and various risk factors among Turkish children.
Materials and Methods: The study involved analyzing the medical records of 83 children born in or admitted to Aksaray Training and Research Hospital, with clinical indications of hip dislocation (HD). The study delved into the relationships between DDH and risk factors such as age under 3 years, female gender, twinning, being the first-born child, C-section delivery, breech presentation, prematurity, positive family history, and the presence of associated abnormalities.
Results: Within the study group, HD was confirmed in 74 children (89%) as Positive HD, whereas 9 children (11%) were ruled out as Negative HD. Subsequently, 12 children (14.4%) were excluded from the initially positive cases, as their diagnosis was confirmed to be paralytic hip dislocation rather than DDH. Ultimately, DDH was verified in 62 children (74.6%). Statistical analyses using the Chi-square test (χ²) and odds ratios (OR) revealed notable associations between DDH and positive family history, female gender, age below 3 years, and the presence of associated abnormalities. The corresponding P values and OR were 0.00 (16.5), 0.002 (3.1), 0.005 (2.6), and 0.042 (1.9) respectively.
Conclusions: Positive family history, female gender, age under 3 years, and the presence of associated abnormalities were associated with an approximate 16-fold, 3-fold, 2.5-fold, and 2-fold increased risk of DDH respectively.
Downloads
References
Jackson JC, Runge MM, Nye NS. Common questions about developmental dysplasia of the hip. Am Fam Physician. 2014;90(12):843-850.
Thomas SR. A review of long-term outcomes for late presenting developmental hip dysplasia. Bone Joint J. 2015;97-B(6):729-733. doi:10.1302/0301-620X.97B6.35395
Sewell MD, Rosendahl K, Eastwood DM. Developmental dysplasia of the hip. BMJ. 2009;339:b4454. Published 2009. doi:10.1136/bmj.b4454.
Adibi A, Karami M, Koohi K, Shirahmad M. Prevalence of different hip sonographic types: A cross-sectional study. Adv Biomed Res. 2015;4:23. Published 2015. doi:10.4103/2277-9175.150390
Storer SK, Skaggs DL. Developmental dysplasia of the hip. Am Fam Physician. 2006;74(8):1310-1316.
Orak MM, Karaman O, Gursoy T, Cagirmaz T, Oltulu I, Muratli HH. Effect of increase in birth weight in a newborn on hip ultrasonography. J Pediatr Orthop B. 2015;24(6):507-510. doi:10.1097/BPB.0000000000000206
Mitchell PD, Redfern RC. The prevalence of dislocation in developmental dysplasia of the hip in Britain over the past thousand years. J Pediatr Orthop. 2007;27(8):890-892. doi:10.1097/bpo.0b013e31815a6091
Rhodes AM, Clarke NM. A review of environmental factors implicated in human developmental dysplasia of the hip. J Child Orthop. 2014;8(5):375-379. doi:10.1007/s11832-014-0615-y
Koşar P, Ergun E, Yiğit H, Gökharman FD, Kosar U. Developmental dysplasia in male infants: risk factors, instability and ultrasound screening. Hip Int. 2011;21(4):409-414. doi:10.5301/HIP.2011.8577
Bozkurt C, Sarıkaya B, Sipahioğlu S, Altay MA, Çetin BV, Bekin Sarıkaya PZ. Effects of developmental dysplasia of the hip screening program on the treatment strategies: A retrospective study from a tertiary care hospital in the southeast region of Turkey. Acta Orthop Traumatol Turc. 2021;55(5):396-401. doi:10.5152/j.aott.2021.20236
Kapicioğlu MIS, Karataş AF, Akkaya M, Korkusuz F, Ömeroğlu H. Six years of experience with the nationwide newborn ultrasonographic hip screening program in Turkey: a considerable change in the type of surgical interventions in developmental dysplasia of the hip [published online ahead of print, 2023]. J Pediatr Orthop B. 2023;10.1097/BPB.0000000000001110. doi:10.1097/BPB.0000000000001110
Szumilas M. Explaining odds ratios [published correction appears in J Can Acad Child Adolesc Psychiatry. 2015 Winter;24(1):58]. J Can Acad Child Adolesc Psychiatry. 2010;19(3):227-229.
Gharedaghi M, Mohammadzadeh A, Zandi B. Comparison of clinical and sonographic prevalence of developmental dysplasia of the hip. Acta Med Iran. 2011;49(1):25-27.
Baronciani D, Atti G, Andiloro F, et al. Screening for developmental dysplasia of the hip: from theory to practice. Collaborative Group DDH Project. Pediatrics. 1997;99(2):E5. doi:10.1542/peds.99.2.e5.
Maxwell SL, Ruiz AL, Lappin KJ, Cosgrove AP. Clinical screening for developmental dysplasia of the hip in Northern Ireland. BMJ. 2002;324(7344):1031-1033. doi:10.1136/bmj.324.7344.1031
Upasani VV, Bomar JD, Parikh G, Hosalkar H. Reliability of plain radiographic parameters for developmental dysplasia of the hip in children. J Child Orthop. 2012;6(3):173-176. doi:10.1007/s11832-012-0406-2
Donaldson JS, Feinstein KA. Imaging of developmental dysplasia of the hip. Pediatr Clin North Am. 1997;44(3):591-614. doi:10.1016/s0031-3955(05)70495-8
Arti H, Mehdinasab SA, Arti S. Comparing results of clinical versus ultrasonographic examination in developmental dysplasia of hip. J Res Med Sci. 2013;18(12):1051-1055.
Cooper A, Evans O, Ali F, Flowers M. A novel method for assessing postoperative femoral head reduction in developmental dysplasia of the hip. J Child Orthop. 2014;8(4):319-324. doi:10.1007/s11832-014-0600-5.
Buonsenso D, Curatola A, Lazzareschi I, et al. Developmental dysplasia of the hip: real world data from a retrospective analysis to evaluate the effectiveness of universal screening. J Ultrasound. 2021;24(4):403-410. doi:10.1007/s40477-020-00463-w.
Loder RT, Skopelja EN. The epidemiology and demographics of hip dysplasia. International Scholarly Research Notices. 2011;2011.
Kamath SU, Bennet GC. Does developmental dysplasia of the hip cause a delay in walking?. J Pediatr Orthop. 2004;24(3):265. doi:10.1097/00004694-200405000-00005
JACOBS JE. Metatarsus varus and hip dysplasia. Clin Orthop. 1960;16:203-213.
Czeizel A, Tusnády G, Vaczó G, Vizkelety T. The mechanism of genetic predisposition in congenital dislocation of the hip. J Med Genet. 1975;12(2):121-124. doi:10.1136/jmg.12.2.121
Pipa-Muñiz I, de Los Llanos Rodríguez-Rodríguez M, Felgueroso-Juliana MB, Riera-Campillo M, González-Herranz P. Displasia del desarrollo de la cadera en niños con trastorno psicomotor. ¿Factor de riesgo para un mal resultado? [Developmental dysplasia of the hip in children with a psychomotor disorder. A risk factor for a poor outcome?]. An Pediatr (Barc). 2016;85(3):142-148. doi:10.1016/j.anpedi.2015.07.028
Clinical practice guideline: early detection of developmental dysplasia of the hip. Committee on Quality Improvement, Subcommittee on Developmental Dysplasia of the Hip. American Academy of Pediatrics. Pediatrics. 2000;105(4 Pt 1):896-905. doi:10.1542/peds.105.4.896
Bjerkreim I, Arseth PH. Congenital dislocation of the hip in Norway. Late diagnosis CDH in the years 1970 to 1974. Acta Paediatr Scand. 1978;67(3):329-332. doi:10.1111/j.1651-2227.1978.tb16329.x
Güler O, Şeker A, Mutlu S, Çerçi MH, Kömür B, Mahiroğulları M. Results of a universal ultrasonographic hip screening program at a single institution. Acta Orthop Traumatol Turc. 2016;50(1):42-48. doi:10.3944/AOTT.2016.15.0024
Shorter D, Hong T, Osborn DA. Cochrane Review: Screening programmes for developmental dysplasia of the hip in newborn infants. Evid Based Child Health. 2013;8(1):11-54. doi:10.1002/ebch.1891
Li SJ, Ford N, Meister K, Bodurtha J. Increased risk of birth defects among children from multiple births. Birth Defects Res A Clin Mol Teratol. 2003;67(10):879-885. doi:10.1002/bdra.10093
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Chronicles of Precision Medical Researchers
![Creative Commons License](http://i.creativecommons.org/l/by-nc-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.