Endoscopic and histopathological findings of upper gastrointestinal tract lesions in pediatric age group
Pediatric upper gastrointestinal tract lesions
DOI:
https://doi.org/10.5281/zenodo.10891249Keywords:
Children, endoscopy, gastrointestinal system, biopsyAbstract
Objective: Upper gastrointestinal (GI) tract endoscopy is a diagnostic procedure utilized to identify pathologies within this region, establish treatment plans, and determine prognoses. This procedure, commonly employed in adults, is now considered safe for use in pediatric patients. The objective of this study was to conduct a retrospective analysis of the results obtained from upper GI endoscopies performed on pediatric patients at a single center.
Methods: During the period between September 2017 and March 2020, we conducted an assessment on a total of 488 patients who were aged between 5 months and 17 years and who underwent upper GI endoscopy and biopsy at the Pediatric Gastroenterology Department of X Hospital.
Results: Over a period of 30 months, a total of 488 pediatric patients underwent upper GI endoscopy procedures, during which biopsies were obtained. The most common complaints reported were abdominal pain and retrosternal burning/bitter water in the mouth. The most frequently observed lesions during the endoscopy procedure were gastritis, duodenitis, and ulcer. Analysis of biopsy specimens revealed that chronic gastritis was the most common lesion found in the stomach, while chronic duodenitis and esophagitis were the most common lesions detected in the duodenum and esophagus, respectively. Helicobacter pylori infection was identified in 195 cases, with ulcers testing positive for H. pylori in 39.1% of these cases. The ulcers resolved after undergoing eradication treatment. Intestinal metaplasia was observed in eight patients, while gastric atrophy was found in three. Sixty-four patients were diagnosed with celiac disease, and as a result, a gluten-free diet was initiated. Additionally, Barret esophagus was detected in four patients.
Conclusion: Endoscopic procedures are becoming increasingly significant in diagnosing pediatric patients due to their ease of use under appropriate sedation and low incidence of complications. These procedures are crucial in ensuring accurate diagnosis and avoiding unnecessary treatment for children
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