GENÇ MİYOKARD İNFARKTÜSLÜ HASTALARDA TRİGLİSERİD/GLUKOZ İNDEKSİ
DOI:
https://doi.org/10.5281/zenodo.10021078Anahtar Kelimeler:
Genç- miyokard infarktüsü- STEMI- NSTEMI- Trigliserid/glukoz indeksiÖzet
Amaç: Akut miyokard infarktüsü (MI), morbidite ve mortalitenin en önemli nedenlerinden birisidir. Genç hastalarda, yaşlılara göre daha az olarak görülmekle beraber oluşum mekanizması ve risk faktörleri yaşlı hastalara göre nispeten farklıdır. Bu çalışmada genç miyokard infarktüsü ile insülin direncini predikte etmede kullanılan kolay hesaplanan bir indeks olan Trigliserid /Glukoz indeksi (TyG) arasında bir ilişki olup olmadığını incelemek amaçlandı.
Gereç ve Yöntem: 65’i 40 yaş altı akut MI geçiren, 65’i kontrol grubu olmak üzere toplam 130 hasta çalışmaya dahil edildi. Retrospektif olarak hastaların klinik durumu, anjiyografi sonuçları, ek hastalıkları, hematolojik ve biyokimyasal belirteçleri ve TyG indexi karşılaştırması yapıldı.
Bulgular: Genç MI geçiren hasta grubunda kontrol grubuna göre glukoz (p=0.001) ve beyaz küre (p<0.001) daha yüksek gözlenirken; yüksek dansiteli lipoprotein (HDL) (p<0.001), albümin (p=0.006) ve hemoglobin (p=0.005) daha düşük izlendi. Genç MI grubu ile kontrol grubu arasında TyG arasında istatiksel olarak anlamlı bir fark izlenmedi.
Sonuç: Bu çalışmada genç MI geçiren hastalar ile TyG arasında bir ilişki gösterilemese de literatürdeki önceki çalışmalar neticesinde yaşlı MI hastalarında kullanımı faydalıdır.
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Referanslar
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