Does Maternal Vitamin D Deficiency Affect Perinatal Outcomes?

Abstract

Aims:

Vitamin D affects placental joining, immune functions, inflammatory response and glucose homeostasis. Vitamin D deficiency can harm both the mother and the fetus' health by boosting the generation of inflammatory cytokines and activating the activation of T- regulatory cells. We aimed to evaluate the perinatal outcomes of vitamin D deficiency.

Materials and Methods:

We evaluated 290 pregnant women who were seen at the Gazi University Medical Faculty Obstetrics and Gynecology Department. The perinatal effects of maternal vitamin D deficiency are studied to learn whether it increases complications during pregnancy such as gestational diabetes mellitus (GDM), preeclampsia, small-for-gestational age (SGA).

Results:

Vitamin D insufficiency and vitamin D deficiency in the pregnant women were established as 91% and 66%, respectively. GDM, preeclampsia, type of delivery, preterm delivery, SGA, median baby birth weight, and median baby birth height also did not differ significantly among the groups (p>0.05).

Conclusions:

Maternal complications that may result from vitamin D deficiency are currently being examined. In our study, we could not demonstrate a correlation between vitamin D and GDM, SGA or preeclampsia.