Can preoperatively measured inflammatory markers in total knee arthroplasty be an early indicator for revision?

Are preoperative inflammatory markers an early indication for revision?


  • Ömer Bozduman Samsun University
  • Ömer Cahit Çıtır Department of Orthopedics and Traumatology, Tokat Gaziosmanpaşa University, Tokat



total knee arthroplasty, Systemic immune-inflammatory index, revision, neutrophil-lymphocyte ratio


Aim: Knee replacement is one of the most commonly performed orthopedic surgeries today. Various prognostic markers are being investigated to reduce the revision rate. In this study, inflammatory markers measured from preoperative blood were evaluated in terms of revision.

Material and Method: 100 patients who underwent Total Knee prosthesis between January 2017 and December 2021 (50 revisions and 50 non-revisions) were included in the study. Systemic immune-inflammatory index (SII), neutrophil-lymphocyte ratio(NLR), lymphocyte-monocyte ratio(LMR) and platelet-lymphocyte ratios(PLR) calculated from the hemograms taken before the first surgery of these patients; were evaluated comparatively between those with and without revision surgery.

Results: The mean age of the patients was 63.98±9.30 (38-80) in patients who underwent revision, and 65.64±9.45 (46-87) in patients who did not undergo revision. There was no significant difference in age and gender distribution between the revised and non-revisioned groups (p>0.05). No significant difference was observed in the number of neutrophils, lymphocytes, and monocytes between the revised and non-revisioned groups (p>0.05). There was no significant difference in SII, NLR, LMR and PLR values between the revised and non-revisioned groups (p>0.05)

Conclusion: SII, NLR, LMR and PLR calculated from the preoperative hemogram taken before total prosthesis surgery, and no significant relationship was found between revision of the knee prosthesis.


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How to Cite

Bozduman, Ömer, & Çıtır , Ömer C. . (2023). Can preoperatively measured inflammatory markers in total knee arthroplasty be an early indicator for revision? Are preoperative inflammatory markers an early indication for revision?. Chronicles of Precision Medical Researchers, 4(1), 64–67.