Seroprevalence of human parvovirus B19 in symptomatic and asymptomatic cases

Seroprevalence of human parvovirus B19

Abstract

Aim: Parvovirus B19 (HPV B19) is a highly contagious virus that is usually transmitted through the respiratory tract. In this study, Parvovirus B19 antibodies were investigated in symptomatic and asymptomatic cases.

Material method: A total of 221 patients were studied for HPV B19 antibodies using the ELISA method between 1998-2001. Findings were analyzed statistically.

Results: It was observed that seropositivity increased with age and peaked in groups over 16 years of age, while seronegativity peaked in the 0-5 age group. When the serological pattern was evaluated according to the clinical stage of the infection, it was observed that the frequency of acute infection was maximum in the 6-10 age group, and there was no acute infection in the control group. When the distribution of acute infection by age was examined, it was observed that anti-HPV B19-IgG positivity was minimum in the 0-5 age group and maximum in the group above 16 years old. In terms of the frequency of IgG positivity, there was a significant difference between the age group above 16 and the age group 6-10 (p<0.05). There was no statistically significant difference in terms of acute infection in the control group (p>0.05). Also, IgM positivity showed a significant difference according to age groups (p >0.05).

Results: According to our results, seropositivity for HPV B19, clinical-stage, acute infection frequency and IgG positivity increase with age. This infection should be kept in mind for optimal treatment management, especially in patients at risk after puberty.